Description

1-o-Hexadecyl-2-o-Acetyl-Sn-Glycerol is a synthetic, enantiomerically pure glycerolipid derivative. This compound serves as a critical intermediate and building block for the synthesis of complex phospholipids and other bioactive lipid molecules. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and advanced material science industries who require high-purity, structurally defined lipid components.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of phospholipid-based drug delivery systems, such as liposomes and lipid nanoparticles (LNPs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway research involving lipid metabolism.
• Cosmetic Formulations: Acts as a high-performance emollient and skin-conditioning agent in premium skincare products.
• Surfactant & Emulsifier Synthesis: Serves as a starting material for producing novel non-ionic surfactants with specific hydrophilic-lipophilic balance (HLB) values.
• Material Science: Building block for creating functionalized lipids used in biosensors, membrane models, and advanced coatings.
• Nutraceuticals: Potential intermediate for specialized lipid-based nutritional supplements.

Basic Information

Product Name	1-o-Hexadecyl-2-o-Acetyl-Sn-Glycerol
CAS No.	77133-35-8
Molecular Formula	C21H42O4
Molecular Weight	358.56 g/mol
Synonyms	1-Hexadecyl-2-acetyl-sn-glycerol; 2-Acetyl-1-hexadecylglycerol; 1-O-Hexadecyl-2-O-acetylglycerol; sn-1-Hexadecyl-2-acetylglycerol; 1-Cetyl-2-acetyl-sn-glycerol; Hexadecyl acetyl glycerol ether; Palmitoyl acetyl glycerol (common name); Glyceryl 1-hexadecyl ether 2-acetate
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-o-Acetyl-Sn-Glycerol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and enantiomeric excess. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support compliance needs for cGMP, ISO, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity	≥ 98.0% (sn-1 isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.