Description

3-Oxo-2-(2-Propynyl)Glutaric Acid Dimethyl Ester is a high-purity, versatile chemical intermediate characterized by its unique keto-ester and propargyl functional groups. This compound is valued for its reactivity, serving as a crucial building block in sophisticated organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic or complex ester frameworks.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in Michael addition reactions, cyclization processes, and as a precursor for various lactones and heterocycles due to its reactive β-ketoester and alkyne moieties.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers and resins.
• Chemical Research & Development: Serves as a versatile starting material in academic and industrial labs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	3-Oxo-2-(2-Propynyl)Glutaric Acid Dimethyl Ester
CAS No.	77087-32-2
Molecular Formula	C10H12O5
Molecular Weight	212.20 g/mol
Synonyms	Dimethyl 3-Oxo-2-(prop-2-yn-1-yl)glutarate; 2-(2-Propynyl)-3-oxoglutaric Acid Dimethyl Ester; Propargyl Oxoglutarate Dimethyl Ester; Dimethyl 2-Propargyl-3-oxoglutarate; 3-Oxo-2-(prop-2-ynyl)pentanedioic Acid Dimethyl Ester; Glutaric Acid, 3-oxo-2-(2-propynyl)-, Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 3-Oxo-2-(2-Propynyl)Glutaric Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets your specified requirements for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.