Description

Ethyl-2-Bromo-4-Methoxyphenylacetate is a high-purity organic ester building block, specifically an α-bromo arylacetate derivative, valued for its versatile reactivity in advanced synthetic chemistry. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It is essential for chemists and process engineers in fine chemical synthesis, offering a reliable route to introduce functionalized phenylacetic acid motifs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules containing modified phenylacetic acid structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators, leveraging the bromine atom for further functionalization.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to the reactive benzyl bromide moiety.
• Ligand and Material Science Research: Serves as a starting material for synthesizing specialized ligands for catalysis or novel organic materials.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in university and industrial research settings.

Basic Information

Product Name	Ethyl-2-Bromo-4-Methoxyphenylacetate
CAS No.	77053-56-6
Molecular Formula	C11H13BrO3
Molecular Weight	273.12 g/mol
Synonyms	Ethyl (2-bromo-4-methoxyphenyl)acetate; 2-Bromo-4-methoxyphenylacetic Acid Ethyl Ester; Ethyl α-Bromo-4-methoxyphenylacetate; (2-Bromo-4-methoxyphenyl)acetic Acid Ethyl Ester; Ethyl 2-Bromo-4-methoxybenzeneacetate; Ethyl (2-Bromo-p-anisyl)acetate; NSC 403120; Ethyl 2-Bromo-4-methoxyphenylacetate
EINECS	Contact for details

Quality Control

Our Ethyl-2-Bromo-4-Methoxyphenylacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.