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Propanoic Acid, 2-Hydroxy-, 1-Methylethyl Ester, (2R)- (9Ci) CAS NO 77027-85-1


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CAS No.:77027-85-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Propanoic Acid, 2-Hydroxy-, 1-Methylethyl Ester, (2R)- (9Ci) is a chiral ester derivative of lactic acid, specifically the (R)-enantiomer of isopropyl lactate. This compound is valued for its role as a high-purity chiral building block and intermediate in the synthesis of optically active pharmaceuticals and fine chemicals. It is essential for research and production in industries requiring precise stereochemical control, such as asymmetric synthesis and advanced material science.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of anti-inflammatory drugs, antiviral agents, and other therapeutics.
  • Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
  • Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including flavors, fragrances, and advanced polymers.
  • Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
  • Material Science: Acts as a monomer or modifying agent in the synthesis of biodegradable polymers and resins with tailored properties.
  • Catalyst and Ligand Preparation: Utilized in the synthesis of chiral catalysts and ligands for homogeneous catalysis applications.

Basic Information

Product Name Propanoic Acid, 2-Hydroxy-, 1-Methylethyl Ester, (2R)- (9Ci)
CAS No. 77027-85-1
Molecular Formula C6H12O3
Molecular Weight 132.16 g/mol
Synonyms (R)-Isopropyl Lactate; (R)-(-)-Isopropyl Lactate; (2R)-2-Hydroxypropanoic Acid 1-Methylethyl Ester; Lactic Acid Isopropyl Ester, (R)-; Isopropyl (R)-(-)-Lactate; (R)-1-Methylethyl 2-Hydroxypropanoate; (R)-2-Hydroxypropionic Acid Isopropyl Ester
EINECS Contact for details

Quality Control

Our (R)-Isopropyl Lactate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing parameters such as chiral purity, chemical assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee (R)
Specific Rotation Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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