Description

p-Nitrophenyl 2-Chloronicotinate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its utility as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its reactive ester and chloropyridine functionalities.
• Peptide Mimetics & PROTACs: Serves as a valuable building block for creating peptide-like structures and Proteolysis Targeting Chimeras (PROTACs) in medicinal chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Academic & Contract Research: Essential for investigative organic synthesis in university laboratories and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	p-Nitrophenyl 2-Chloronicotinate
CAS No.	76980-32-0
Molecular Formula	C12H7ClN2O4
Molecular Weight	278.65 g/mol
Synonyms	4-Nitrophenyl 2-chloropyridine-3-carboxylate; 2-Chloronicotinic Acid 4-Nitrophenyl Ester; 2-Chloro-3-pyridinecarboxylic Acid 4-Nitrophenyl Ester; 3-Pyridinecarboxylic Acid, 2-chloro-, 4-nitrophenyl ester; p-Nitrophenyl 2-chloro-3-pyridinecarboxylate; 2-Chloronicotinoyl 4-Nitrophenyl Ester; (2-Chloropyridin-3-yl)(4-nitrophenyl) methanone (tautomeric form)
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl 2-Chloronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.