Description

(3R,5S,6'As,10'Ar)-5-(3-Furyl)-4,5,6',6'Aβ-Tetrahydro-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3',10'(5'H,9'H)-Trione is a complex, high-purity spirocyclic furanone derivative with a defined stereochemistry. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) or anti-inflammatory pathways.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or reagent in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies due to its unique polycyclic furanone scaffold.
• Fine Chemical Production: Serves as a building block for the manufacture of specialty chemicals, agrochemicals, and high-performance materials requiring specific stereochemistry.
• Academic & Institutional Research: Used in chemical research for methodology development and the study of novel reaction mechanisms involving spirocyclic systems.
• Process Chemistry Development: Investigated for scalable synthesis routes in the pilot-scale production of target molecules.

Basic Information

Item	Details
Product Name	(3R,5S,6'As,10'Ar)-5-(3-Furyl)-4,5,6',6'Aβ-Tetrahydro-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3',10'(5'H,9'H)-Trione
CAS No.	76902-35-7
Molecular Formula	C20H16O6
Molecular Weight	352.34 g/mol
Synonyms	5-(3-Furyl)-4,5,6',6'a-tetrahydro-8'a-methylspiro[furan-3(2H),7'(8'H)-naphtho[1,8a-c]furan]-2,3',10'(5'H,9'H)-trione; Spiro[naphtho[1,8a-c]furan-7'(8'H),3'-furan]-2,3',10'(5'H,9'H)-trione, 5-(3-furanyl)-4,5,6',6'a-tetrahydro-8'a-methyl-, (3R,5S,6'aS,10'aR)-; (3R,5S,6'aS,10'aR)-5-(3-Furyl)-4,5,6',6'a-tetrahydro-8'a-methylspiro[furan-3(2H),7'(8'H)-naphtho[1,8a-c]furan]-2,3',10'(5'H,9'H)-trione; CAS 76902-35-7
EINECS	Contact for details

Quality Control

Our (3R,5S,6'As,10'Ar)-5-(3-Furyl)-4,5,6',6'Aβ-Tetrahydro-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3',10'(5'H,9'H)-Trione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.