Description

1',3'-Dihydrospiro[Cyclohexane-1,2'-[2H]Imidazo[4,5-B]Pyridine] is a sophisticated spirocyclic organic compound featuring a fused imidazopyridine core, offering a unique three-dimensional molecular scaffold. This structure is highly valuable for medicinal chemistry research, particularly in the development of novel small-molecule therapeutics targeting central nervous system (CNS) disorders and other complex biological pathways. It serves as a critical advanced pharmaceutical intermediate for research organizations, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis due to its complex, rigid spirocyclic architecture.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and receptor interactions.
• Process Development: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in universities and research institutes for investigations into novel heterocyclic chemistry and bioactivity.

Basic Information

Product Name	1',3'-Dihydrospiro[Cyclohexane-1,2'-[2H]Imidazo[4,5-B]Pyridine]
CAS No.	76902-24-4
Molecular Formula	C12H15N3
Molecular Weight	201.27 g/mol
Synonyms	1',3'-Dihydrospiro[cyclohexane-1,2'-[2H]imidazo[4,5-b]pyridine]; Spiro[cyclohexane-1,2'-imidazo[4,5-b]pyridine]; 1H,3'H-Spiro[cyclohexane-1,2'-imidazo[4,5-b]pyridine]; 76902-24-4; Spirocyclic imidazopyridine; 2H-Imidazo[4,5-b]pyridine, 1',3'-dihydrospiro[cyclohexane-1,2'-
EINECS	Contact for details

Quality Control

Every batch of 1',3'-Dihydrospiro[Cyclohexane-1,2'-[2H]Imidazo[4,5-B]Pyridine] is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full analytical data from techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.