Description

(6E)-3-Ethoxy-6-(Trimethylsilyloxymethylidene)Cyclohex-2-En-1-One CAS NO 76881-18-0 is a specialized, high-value organosilicon intermediate featuring a unique enone structure with ethoxy and trimethylsilyl protecting groups. This compound is critical for synthetic organic chemists as a versatile building block in complex multi-step synthesis, enabling precise molecular construction. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the total synthesis of complex natural products and novel drug candidates, particularly in constructing functionalized cyclohexenone cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Advanced Material Precursor: Serves as a monomer or intermediate in the synthesis of specialty polymers and organic electronic materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including studies on cycloaddition reactions and stereoselective transformations.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	(6E)-3-Ethoxy-6-(Trimethylsilyloxymethylidene)Cyclohex-2-En-1-One
CAS No.	76881-18-0
Molecular Formula	C₁₃H₂₄O₃Si
Molecular Weight	256.42 g/mol
Synonyms	3-Ethoxy-6-[(trimethylsilyloxy)methylene]-2-cyclohexen-1-one; 6-[(Trimethylsilyloxy)methylene]-3-ethoxy-2-cyclohexen-1-one; (6E)-3-Ethoxy-6-[(trimethylsilyloxy)methylene]cyclohex-2-en-1-one; TMS-protected 3-ethoxy-6-hydroxymethylidenecyclohex-2-enone; 76881-18-0; Ethoxy TMS enol ether cyclohexenone
EINECS	Contact for details

Quality Control

Our production of (6E)-3-Ethoxy-6-(Trimethylsilyloxymethylidene)Cyclohex-2-En-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.