Description

(E)-Ethyl 5-(4-Methoxyphenyl)-3-Oxopent-4-Enoate is a high-purity, versatile organic intermediate characterized by its α,β-unsaturated ketone (enone) and ester functional groups. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific molecular scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing chalcone or diarylpentanoid motifs with potential biological activity.
• Organic Synthesis Building Block: Utilized in Michael addition reactions, cyclization processes, and other carbon-carbon bond-forming transformations to construct complex heterocyclic and acyclic structures.
• Agrochemical Research: Serves as a starting material for developing novel herbicides, fungicides, and plant growth regulators that leverage its specific phenyl and enone chemistry.
• Material Science & Chemical Research: Used in academic and industrial R&D for exploring new polymers, ligands, or organic electronic materials due to its conjugated system and reactive sites.
• Flavor & Fragrance Synthesis: Acts as an intermediate for creating specific aromatic compounds where the methoxyphenyl group contributes to desired olfactory properties.

Basic Information

Product Name	(E)-Ethyl 5-(4-Methoxyphenyl)-3-Oxopent-4-Enoate
CAS No.	76842-83-6
Molecular Formula	C14H16O4
Molecular Weight	248.28 g/mol
Synonyms	Ethyl (E)-5-(4-Methoxyphenyl)-3-oxopent-4-enoate; 4-Pentenoic acid, 5-(4-methoxyphenyl)-3-oxo-, ethyl ester, (E)-; Ethyl 3-oxo-5-(4-methoxyphenyl)-4-pentenoate; (E)-Ethyl 3-oxo-5-(p-methoxyphenyl)-4-pentenoate; Ethyl (E)-3-oxo-5-(4-methoxyphenyl)pent-4-enoate; p-Methoxyphenyl chalcone ethyl ester derivative; 4-Methoxychalcone β-keto ester
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 5-(4-Methoxyphenyl)-3-Oxopent-4-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.