Description

tert-Butyldimethyl(2-Propynyloxy)Silane is a specialized organosilicon compound featuring a reactive propargyl ether group attached to a silicon center. This unique structure makes it a valuable silylating agent and a versatile building block in advanced organic synthesis and materials science. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for the protection of alcohols and the synthesis of complex molecular architectures.

Application

• Protecting Group Chemistry: Used as a silylating agent for the temporary protection of hydroxyl groups in multi-step organic synthesis, particularly in the production of complex drug intermediates.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Agrochemical Synthesis: Employed in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the creation of specialty silicones, resins, and advanced polymeric materials.
• Surface Modification: Utilized to modify the surface properties of inorganic materials like silica or metals, imparting specific functional characteristics.
• Click Chemistry: The propargyloxy group can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling its use in bioconjugation and polymer functionalization.

Basic Information

Product Name	tert-Butyldimethyl(2-Propynyloxy)Silane
CAS No.	76782-82-6
Molecular Formula	C9H20OSi
Molecular Weight	172.34 g/mol
Synonyms	2-Propynyloxy-tert-butyldimethylsilane; tert-Butyldimethyl(prop-2-yn-1-yloxy)silane; (2-Propynyloxy)-tert-butyldimethylsilane; Propargyloxy-tert-butyldimethylsilane; TBDMS Propargyl Ether; TBDMSOCH2C≡CH; tert-Butyldimethylsilyl Propargyl Ether
EINECS	Contact for details

Quality Control

Our tert-Butyldimethyl(2-Propynyloxy)Silane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, NMR, and FTIR to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.