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n-Methyl-n-[3-(Trimethylsilyl)-2-Propynyl]Benzenemethanamine CAS NO 76681-44-2


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CAS No.:76681-44-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Methyl-n-[3-(Trimethylsilyl)-2-Propynyl]Benzenemethanamine is a specialized organosilicon amine compound featuring a unique trimethylsilyl-protected propargyl group. This structural motif makes it a valuable high-purity building block in advanced organic synthesis, particularly for applications requiring precise molecular architecture. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring silicon-containing or alkyne-functionalized amine backbones.
  • Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, including those for asymmetric synthesis and cross-coupling reactions.
  • Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, silicones, and hybrid organic-inorganic materials.
  • Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and plant growth regulators.
  • Click Chemistry: The protected alkyne group makes it a suitable component for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions in bioconjugation and polymer chemistry.

Basic Information

Product Name n-Methyl-n-[3-(Trimethylsilyl)-2-Propynyl]Benzenemethanamine
CAS No. 76681-44-2
Molecular Formula C15H25NSi
Molecular Weight 247.45 g/mol
Synonyms N-Methyl-N-(3-(trimethylsilyl)prop-2-yn-1-yl)benzylamine; Benzyl(methyl)[3-(trimethylsilyl)-2-propynyl]amine; N-Benzyl-N-methyl-3-(trimethylsilyl)prop-2-yn-1-amine; 1-(Benzyl(methyl)amino)-3-(trimethylsilyl)prop-2-yne; N-Methyl-N-(3-trimethylsilyl-2-propynyl)benzylamine
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Quality Control

Our production of n-Methyl-n-[3-(Trimethylsilyl)-2-Propynyl]Benzenemethanamine adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the exacting standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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