Description

4-Trimethylsilylbutanoic Acid Sodium Salt is a versatile organosilicon compound that serves as a key intermediate in advanced organic synthesis. Its value lies in its dual functionality, combining a reactive carboxylic acid salt with a hydrolytically stable trimethylsilyl protecting group. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of silicon-containing active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing silicon-substituted carboxylic acids and related drug candidates.
• Peptide Synthesis: Used as a protected or modified amino acid analog in peptide research.
• Material Science: Precursor for surface modification agents and silicon-functionalized polymers.
• Organic Synthesis: Serves as a stable carbanion equivalent or nucleophile in C-C bond-forming reactions.
• Ligand Synthesis: Intermediate for creating specialized ligands used in catalysis.
• Analytical Chemistry: Potential derivatization agent for gas chromatography (GC) analysis of complex mixtures.

Basic Information

Product Name	4-Trimethylsilylbutanoic Acid Sodium Salt
CAS No.	76681-38-4
Molecular Formula	C7H15NaO2Si
Molecular Weight	182.27 g/mol
Synonyms	Sodium 4-(Trimethylsilyl)butanoate; 4-(Trimethylsilyl)butyric Acid Sodium Salt; Sodium 4-(Trimethylsilyl)butyrate; Butanoic acid, 4-(trimethylsilyl)-, sodium salt (1:1); 4-TMS-Butyric Acid Sodium Salt; (3-Carboxypropyl)trimethylsilane Sodium Salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. We provide comprehensive analytical data including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.