Description

3-Chloro-2-Trimethylsiloxypropene is a versatile organosilicon reagent featuring a reactive chloro and a protected enol ether functional group. This compound is a valuable synthetic intermediate, enabling the introduction of trimethylsilyl-protected enolate equivalents and other functionalized propene units into complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex carbon skeletons and introducing functional handles for further derivatization.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemicals, and advanced materials where precise control over molecular architecture is required.
• Organometallic Chemistry: Serves as a precursor for generating reactive organometallic species used in cross-coupling reactions and other catalytic transformations.
• Polymer Science: Can be used as a monomer or co-monomer in the development of specialty polymers with tailored properties.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry, enabling new routes to complex molecules in both academic and industrial research settings.

Basic Information

Product Name	3-Chloro-2-Trimethylsiloxypropene
CAS No.	76634-95-2
Molecular Formula	C6H13ClOSi
Molecular Weight	164.70 g/mol
Synonyms	1-Chloro-3-(trimethylsilyloxy)-1-propene; 3-Chloro-2-(trimethylsiloxy)-1-propene; 2-(Trimethylsiloxy)-3-chloropropene; 3-Chloro-2-(trimethylsilyloxy)propene; (3-Chloro-2-propenyloxy)trimethylsilane; Trimethyl[(3-chloro-2-propenyl)oxy]silane; 3-Chloro-2-(trimethylsilyloxy)prop-1-ene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Trimethylsiloxypropene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.