Description

4-Cyanophenyl Hydrogen Carbonate is a specialized organic carbonate ester of significant interest in advanced chemical synthesis. This compound serves as a versatile and reactive intermediate, enabling the controlled introduction of the 4-cyanophenyl carbonate moiety into target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in prodrug strategies and carbonate-linked drug conjugates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the cyanophenyl group is a critical pharmacophore.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers, such as polycarbonates with specific functional groups for material science applications.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for introducing protected phenol or carbonate functionalities under mild conditions.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material in the synthesis of advanced electronic materials requiring cyanophenyl components.
• Cross-coupling Reactions: Useful substrate in palladium-catalyzed cross-coupling reactions for creating complex biaryl systems.

Basic Information

Product Name	4-Cyanophenyl Hydrogen Carbonate
CAS No.	76590-50-6
Molecular Formula	C8H5NO3
Molecular Weight	163.13 g/mol
Synonyms	4-Cyanophenyl carbonic acid; p-Cyanophenyl hydrogen carbonate; Carbonochloridic acid, 4-cyanophenyl ester; (4-Cyanophenoxy)formic acid; 4-Cyanophenol carbonate; 4-Cyanophenyl carbonate; 4-Cyanophenyloxyformic acid; p-Cyanophenoxyformic acid
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for our 4-Cyanophenyl Hydrogen Carbonate. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). Our standard quality commitment includes rigorous identity confirmation via spectroscopic methods and precise purity determination using chromatographic techniques. Certificates of Analysis detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.