Description

2,3-o-Carbonyl-α-D-Mannopyranose is a specialized carbohydrate derivative featuring a cyclic carbonate group bridging the 2 and 3 positions of the sugar ring. This compound is significant as a key chiral intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Used in the study and synthesis of complex carbohydrates, glycoconjugates, and glycomimetics for biological evaluation.
• Protecting Group Strategy: The cyclic carbonate moiety acts as a protective group for diols in multi-step synthetic routes, offering stability under specific conditions.
• Bioconjugation: Employed in the modification of biomolecules, such as proteins or peptides, to alter their properties or create targeted drug delivery systems.
• Catalyst and Ligand Development: Utilized as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or cross-linking agent for the development of novel biodegradable polymers with specific functionalities.

Basic Information

Product Name	2,3-o-Carbonyl-α-D-Mannopyranose
CAS No.	76548-27-1
Molecular Formula	C7H10O7
Molecular Weight	206.15 g/mol
Synonyms	2,3-Cyclic Carbonate of α-D-Mannopyranose; α-D-Mannopyranose 2,3-cyclic carbonate; 1,6-Anhydro-2,3-O-carbonyl-β-D-mannopyranose (tautomeric form); D-Mannose 2,3-carbonate; 2,3-O-Carbonyl-α-D-mannose; 76548-27-1; α-D-Mannopyranose cyclic 2,3-carbonate
EINECS	Contact for details

Quality Control

Our 2,3-o-Carbonyl-α-D-Mannopyranose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.