Description

1,2-o-Isopropylidene-β-D-Fructofuranose 3,4,6-Triacetate is a key protected carbohydrate derivative, serving as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a stable, selectively protected fructose scaffold for the controlled introduction of functional groups, enabling the synthesis of complex molecules with high stereochemical fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing nucleoside analogs, glycosidase inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Glycoscience Research: Used as a protected starting material for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Chiral Pool Synthesis: Serves as a versatile chiral template for constructing enantiomerically pure natural products and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Employed in the research and production of advanced, sugar-based pesticides and plant growth regulators.
• Fine Chemical Manufacturing: Acts as a specialized intermediate for producing high-value flavors, fragrances, and specialty chemicals.
• Diagnostic Reagent Synthesis: Used in the development of labeled sugars and probes for biochemical assays and diagnostic kits.

Basic Information

Product Name	1,2-o-Isopropylidene-β-D-Fructofuranose 3,4,6-Triacetate
CAS No.	76512-89-5
Molecular Formula	C15H22O9
Molecular Weight	346.33 g/mol
Synonyms	1,2-O-Isopropylidene-β-D-fructofuranose 3,4,6-triacetate; 3,4,6-Tri-O-acetyl-1,2-O-isopropylidene-β-D-fructofuranose; 1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose triacetate (common misnomer); D-Fructose, 1,2-O-(1-methylethylidene)-, 3,4,6-triacetate; Isopropylidene fructofuranose triacetate; Protected fructose triacetate; Acetylated isopropylidene fructose
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-β-D-Fructofuranose 3,4,6-Triacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.