Description

(2S,3S,4S,5S)-3-(Butyryloxy)-5-Methyltetrahydrofuran-2,4-Diyl Dipropionate is a high-purity, stereochemically defined chemical intermediate of significant interest in advanced organic synthesis. Its precise chiral structure makes it a valuable building block for the development of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers requiring a reliable source of a specific enantiomer to ensure the efficacy and safety of final active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, including potential antiviral or antibiotic compounds.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Process Chemistry Development: Serves as a critical reference standard or intermediate during the research, development, and scale-up of new chemical entities (NCEs).
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where specific stereochemistry is required for functional performance.
• Academic & Industrial Research: A valuable tool for chemists in both academic and industrial R&D settings exploring new synthetic methodologies or bioactive compounds.

Basic Information

Product Name	(2S,3S,4S,5S)-3-(Butyryloxy)-5-Methyltetrahydrofuran-2,4-Diyl Dipropionate
CAS No.	76497-54-6
Molecular Formula	C17H26O7
Molecular Weight	342.39 g/mol
Synonyms	1,2,3,4-Tetrahydro-5-methyl-3-(1-oxobutoxy)-2,4-bis(1-oxopropoxy)furan, (2S,3S,4S,5S)-rel-; 5-Methyltetrahydrofuran-2,3,4-triyl tributyrate (isomeric); Butyric acid, ester with 5-methyltetrahydro-2,3,4-furantriol; Tetrahydro-5-methyl-3-(1-oxobutoxy)-2,4-bis(1-oxopropoxy)furan; A chiral tetrahydrofuran triester derivative.
EINECS	Contact for details

Quality Control

Our production of (2S,3S,4S,5S)-3-(Butyryloxy)-5-Methyltetrahydrofuran-2,4-Diyl Dipropionate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting specifications for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.