Description

1,3-Dioxolo[4,5-B]Pyridine, 6-Bromo- CAS NO 76470-56-9 is a high-purity brominated heterocyclic compound featuring a fused dioxole ring system. This specialized intermediate is critical for advanced organic synthesis, particularly in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides due to its reactive bromine substituent and heterocyclic core.
• Material Science: Serves as a precursor for creating functionalized organic ligands and monomers for advanced polymers.
• Academic & R&D: Essential for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Chemical Synthesis: Employed in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyridine-dioxole moiety into larger molecules.

Basic Information

Product Name	1,3-Dioxolo[4,5-B]Pyridine, 6-Bromo-
CAS No.	76470-56-9
Molecular Formula	C7H4BrNO2
Molecular Weight	214.02 g/mol
Synonyms	6-Bromo-1,3-dioxolo[4,5-b]pyridine; 6-Bromopyrido[3,4-d][1,3]dioxole; 6-Bromo-2H,4H-[1,3]dioxolo[4,5-b]pyridine; 6-Bromo-1,3-benzodioxolo[4,5-b]pyridine; 6-Bromopyrido[2,3-d][1,3]dioxole; 76470-56-9; 6-Bromo-[1,3]dioxolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolo[4,5-B]Pyridine, 6-Bromo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.