Description

1,3-Dioxolo[4,5-B]Pyridine-6-Thiol is a specialized heterocyclic building block featuring a fused dioxole ring and a reactive thiol group. This unique molecular structure makes it a valuable intermediate for synthesizing complex pharmacologically active compounds and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme activity and biological pathways due to its reactive thiol moiety.

Basic Information

Product Name	1,3-Dioxolo[4,5-B]Pyridine-6-Thiol
CAS No.	76470-54-7
Molecular Formula	C7H5NO2S
Molecular Weight	167.19 g/mol
Synonyms	6-Mercapto-1,3-dioxolo[4,5-b]pyridine; 1,3-Dioxolo[4,5-b]pyridine-6-thiol; 6-Pyridinethiol, 1,3-dioxolo[4,5-b]-; 6-Thioxo-6,7-dihydro-[1,3]dioxolo[4,5-b]pyridine; 76470-54-7; 6-Mercapto-[1,3]dioxolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolo[4,5-B]Pyridine-6-Thiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.