Description

Dolo-Buscopan Suppository CAS NO 76422-10-1 is a pharmaceutical formulation designed for rectal administration, combining the analgesic properties of a pain reliever with the antispasmodic action of scopolamine butylbromide. This product matters for its targeted efficacy in providing rapid relief from acute abdominal pain, cramps, and spasms associated with gastrointestinal and genitourinary conditions. It is primarily needed by pharmaceutical manufacturers, compounding pharmacies, and healthcare distributors serving hospitals and clinics globally.

Application

• Pharmaceutical Manufacturing: Primary use in the formulation of ready-to-market rectal suppositories for over-the-counter (OTC) and prescription markets.
• Symptomatic Relief: Effective management of symptoms related to irritable bowel syndrome (IBS), biliary colic, and renal colic.
• Gastrointestinal Disorders: Treatment of abdominal pain and spasms caused by gastritis, enteritis, or other functional gastrointestinal disturbances.
• Gynecological Applications: Alleviation of dysmenorrhea (menstrual cramps) and pain associated with pelvic inflammatory conditions.
• Pre-procedural Care: Used to reduce spasms and discomfort prior to certain endoscopic or diagnostic procedures.
• Hospital & Clinical Formulary: Inclusion in institutional drug formularies for in-patient and emergency care.

Basic Information

Product Name	Dolo-Buscopan Suppository
CAS No.	76422-10-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Scopolamine Butylbromide and Analgesic Suppository; Hyoscine Butylbromide with Paracetamol Suppository; Buscopan Compositum Suppositories; Antispasmodic-Analgesic Rectal Suppository; Butylscopolamine Bromide Combination Suppository; IBS Relief Suppository; Abdominal Antispasmodic Suppository
EINECS	Contact for details

Quality Control

Our Dolo-Buscopan Suppository is manufactured under strict Good Manufacturing Practices (GMP) guidelines, ensuring consistency and reliability for pharmaceutical applications. Each batch undergoes rigorous quality testing, including assay, uniformity of dosage units, dissolution, and microbial limits, to ensure compliance with in-house and international pharmacopeial standards. A comprehensive Certificate of Analysis (COA) documenting all critical quality attributes is available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature between 15°C and 25°C (59°F and 77°F). Do not freeze. Keep away from excessive heat and moisture to maintain product integrity and shelf life.

Specification

Item	Specification
Description	White to off-white, uniform suppository
Identification (HPLC)	Complies
Assay (Active Ingredients)	90.0% - 110.0% of label claim
Uniformity of Dosage Units	Complies with Ph. Eur./USP
Dissolution	NLT 80% in 45 minutes
Melting Range	33°C - 36°C
Microbial Limits	Absence of specified pathogens
Total Aerobic Microbial Count	< 100 CFU/g
Total Combined Yeasts/Molds Count	< 10 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.