Description

Ethyl 2-Isocyanatobenzoate is a versatile aromatic isocyanate ester, a key building block in organic synthesis. This compound is valued for its reactive isocyanate group, which readily undergoes addition and cyclization reactions to form heterocyclic structures and functional polymers. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of benzimidazole, quinazolinone, and other nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its ability to form urea and carbamate linkages.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of polyurethanes, polyureas, and specialty coatings with tailored properties.
• Chemical Research & Development: Employed in medicinal chemistry for library synthesis and in academic research for exploring new organic reaction methodologies.
• Dye & Pigment Industry: Acts as an intermediate in the manufacture of complex organic colorants and photographic chemicals.

Basic Information

Product Name	Ethyl 2-Isocyanatobenzoate
CAS No.	76393-16-3
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	Ethyl 2-Isocyanatobenzoate; 2-Isocyanatobenzoic Acid Ethyl Ester; Benzoic acid, 2-isocyanato-, ethyl ester; Ethyl o-isocyanatobenzoate; Ethyl anthranilate N-carboxy anhydride (precursor form)
EINECS	Contact for details

Quality Control

Our Ethyl 2-Isocyanatobenzoate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace moisture and isocyanate content, which are critical for sensitive synthetic applications. Our quality commitment supports cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and sources of ignition. Isolate from amines, alcohols, water, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Isocyanate Content (Titration)	≥ 20.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.