Description

Methyl 5,6,7,8-Tetrahydroquinoline-5-Carboxylate is a high-value, heterocyclic organic building block and intermediate of significant interest in advanced chemical synthesis. Its partially saturated quinoline core with an ester functional group makes it a versatile precursor for the development of complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a crucial building block for developing advanced pesticides, herbicides, and fungicides with novel modes of action.
• Fine Chemical Production: Used in the synthesis of complex dyes, pigments, and other specialty chemicals requiring a functionalized tetrahydroquinoline scaffold.
• Material Science Research: Investigated as a precursor for organic electronic materials, ligands for catalysis, and other advanced functional materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Methyl 5,6,7,8-Tetrahydroquinoline-5-Carboxylate
CAS No.	76384-35-5
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	5,6,7,8-Tetrahydroquinoline-5-carboxylic acid methyl ester; Methyl 5,6,7,8-tetrahydro-5-quinolinecarboxylate; 5-Methoxycarbonyl-5,6,7,8-tetrahydroquinoline; 5-Carbomethoxy-5,6,7,8-tetrahydroquinoline; Methyl 1,2,3,4-tetrahydroquinoline-5-carboxylate (tautomeric form); 5-(Methoxycarbonyl)-5,6,7,8-tetrahydroquinoline; Tetrahydroquinoline-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Production of Methyl 5,6,7,8-Tetrahydroquinoline-5-Carboxylate is supported by in-process controls and final release testing via modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.