Description

2-Acetamido-1,3,4,6-Tetra-o-Acetyl-2-Deoxymannopyranose is a key acetylated monosaccharide derivative, specifically a protected form of N-acetyl-D-mannosamine. This compound is a critical advanced intermediate in the synthesis of complex carbohydrates and glycoconjugates, prized for its role in introducing the mannosamine moiety with precise stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing glycoprotein-based therapeutics, synthetic vaccines, and diagnostic tools.

Application

• Glycochemistry & Glycobiology Research: A fundamental building block for the chemical and enzymatic synthesis of oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the production of sialic acid derivatives and other bioactive carbohydrate-based drugs.
• Vaccine Development: Used in the synthesis of carbohydrate antigens for conjugate vaccines targeting bacterial and viral pathogens.
• Diagnostic Reagents: Employed in the manufacture of labeled sugars and probes for studying cell-surface interactions and glycosylation patterns.
• Enzyme Substrate Studies: Acts as a substrate or inhibitor for glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific carbohydrate recognition properties.

Basic Information

Product Name	2-Acetamido-1,3,4,6-Tetra-o-Acetyl-2-Deoxymannopyranose
CAS No.	76375-61-6
Molecular Formula	C16H23NO10
Molecular Weight	389.36 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-mannopyranose; N-Acetyl-1,3,4,6-tetra-O-acetyl-α-D-mannosamine; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-mannopyranose; Ac4ManNAc; α-D-ManNAc(Ac)4; Peracetylated N-Acetylmannosamine; Tetraacetylated N-Acetyl-D-mannosamine; 2-Deoxy-2-acetamido-1,3,4,6-tetra-O-acetyl-α-D-mannopyranose
EINECS	Contact for details

Quality Control

Our high-purity 2-Acetamido-1,3,4,6-Tetra-o-Acetyl-2-Deoxymannopyranose is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	[α]²⁰D: +40° to +50° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.