Description

4-Hydroperoxydechlorocyclophosphamide is a key activated metabolite and synthetic intermediate derived from the cyclophosphamide class of compounds. This compound matters for its critical role in pharmaceutical research, particularly in the study of anticancer drug metabolism and mechanism of action. It is primarily needed by research institutions and pharmaceutical companies engaged in oncology drug development, metabolite identification, and analytical method validation.

Application

• Pharmaceutical Research & Development: As a reference standard and synthetic intermediate in the development and study of cyclophosphamide-based anticancer therapies.
• Metabolite Studies: Used to investigate the metabolic pathways, activation, and detoxification mechanisms of oxazaphosphorine drugs.
• Analytical Chemistry: Serves as a high-purity calibrant and standard for HPLC, LC-MS, and other analytical techniques in bioanalytical and pharmacokinetic studies.
• Biochemical Research: Employed in studies of DNA alkylation, apoptosis induction, and cellular response to chemotherapeutic agents.
• Toxicology & Safety Assessment: Utilized to understand the toxicological profile and side effects associated with active metabolites of chemotherapeutic drugs.

Basic Information

Product Name	4-Hydroperoxydechlorocyclophosphamide
CAS No.	76353-74-7
Molecular Formula	C7H14Cl2N2O3P
Molecular Weight	279.08 g/mol
Synonyms	4-Hydroperoxydechlorocyclophosphamide; 4-HP-DC-CPA; 4-Hydroperoxy-2-de(chloroethyl)cyclophosphamide; 4-Hydroperoxy-2-dechloroethylcyclophosphamide; NSC 370955; Peroxydechlorocyclophosphamide; 4-Hydroperoxy Cyclophosphamide Derivative
EINECS	Contact for details

Quality Control

Our 4-Hydroperoxydechlorocyclophosphamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.