Description

Cyclohexaneacetic Acid,4-Amino-,Ethyl Ester,trans- CAS NO 76308-28-6 is a specialized chiral intermediate featuring a trans-configured cyclohexane ring with amino and ester functional groups. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise stereochemistry essential for pharmaceutical efficacy. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.
• Academic and Industrial Research: A valuable compound for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	Cyclohexaneacetic Acid,4-Amino-,Ethyl Ester,trans-
CAS No.	76308-28-6
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	trans-4-Aminocyclohexaneacetic Acid Ethyl Ester; Ethyl trans-4-Aminocyclohexylacetate; trans-Ethyl 4-Aminocyclohexylacetate; (trans-4-Aminocyclohexyl)acetic Acid Ethyl Ester; 4-Aminocyclohexaneacetic Acid Ethyl Ester, trans-; UNII-6J8Z1L0Q3M; 6J8Z1L0Q3M; Ethyl (trans-4-aminocyclohexyl)acetate
EINECS	Contact for details

Quality Control

Our Cyclohexaneacetic Acid,4-Amino-,Ethyl Ester,trans- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.