Description

Propanoic Acid, 3,3-Dibromo-2-Oxo-, Ethyl Ester is a specialized brominated keto-ester compound, identified by CAS NO 76179-25-4, serving as a versatile synthetic intermediate in advanced organic synthesis. Its unique structure, featuring two bromine atoms adjacent to a carbonyl group, makes it a valuable electrophile and building block for constructing complex molecular frameworks. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functional complexity into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring brominated or heterocyclic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the dibromo-ketoester group can be leveraged for further functionalization.
• Fine Chemical Production: Serves as a building block for specialty chemicals, dyes, and functional materials requiring specific bromine substitution patterns.
• Academic & Industrial R&D: Employed in method development and discovery chemistry for studying new reactions involving halogenated compounds and carbonyl chemistry.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the presence of reactive carbon-bromine bonds.
• Nucleophilic Substitution: The bromine atoms are excellent leaving groups, facilitating nucleophilic substitution reactions to install a wide range of functional groups.

Basic Information

Product Name	Propanoic Acid, 3,3-Dibromo-2-Oxo-, Ethyl Ester
CAS No.	76179-25-4
Molecular Formula	C5H6Br2O3
Molecular Weight	273.91 g/mol
Synonyms	Ethyl 3,3-dibromo-2-oxopropanoate; Ethyl 2-oxo-3,3-dibromopropanoate; 3,3-Dibromo-2-oxopropionic Acid Ethyl Ester; Dibromopyruvic Acid Ethyl Ester; Ethyl Dibromopyruvate; 2-Oxo-3,3-dibromopropanoic Acid Ethyl Ester; Ethyl α,α-dibromopyruvate; DBPE
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3,3-Dibromo-2-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.