Description

2,2-Dimethyl-Propionic Acid (1R,5R)-4-Hydroxy-6,6-Dimethyl-Bicyclo[3.1.1]Hept-2-En-2-Ylmethyl Ester is a high-purity, chiral bicyclic ester derivative of pivalic acid, serving as a critical advanced intermediate in sophisticated organic synthesis. Its defined stereochemistry and complex molecular architecture make it an invaluable building block for constructing pharmacologically active molecules with high specificity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in the areas of terpene-based therapeutics and chiral drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for terpene-derived drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated building block in stereoselective organic synthesis to introduce complex, rigid bicyclic structures.
• Fragrance & Flavor Chemistry: Serves as a precursor for high-value aroma chemicals, leveraging its modified pinane skeleton for unique olfactory properties.
• Agrochemical Research: Employed in the synthesis of advanced, biologically active molecules for crop protection and agrochemical discovery programs.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: Used in chemical research for methodological studies in esterification, chiral resolution, and complex molecule construction.

Basic Information

Product Name	2,2-Dimethyl-Propionic Acid (1R,5R)-4-Hydroxy-6,6-Dimethyl-Bicyclo[3.1.1]Hept-2-En-2-Ylmethyl Ester
CAS No.	76163-97-8
Molecular Formula	C15H24O3
Molecular Weight	252.35 g/mol
Synonyms	(1R,5R)-4-Hydroxy-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ylmethyl 2,2-dimethylpropanoate; 4-Hydroxy-2-pinen-10-yl pivalate; (1R,5R)-(-)-Myrtenyl pivalate; (-)-Myrtenyl pivalate; (1R,5R)-4-Hydroxy-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ylmethyl pivalate; Pivalic acid myrtenyl ester; Bicyclo[3.1.1]hept-2-ene-2-methanol, 4-hydroxy-6,6-dimethyl-, 2,2-dimethylpropanoate, (1R,5R)-
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-Propionic Acid (1R,5R)-4-Hydroxy-6,6-Dimethyl-Bicyclo[3.1.1]Hept-2-En-2-Ylmethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.