Description

Cyclopropanecarboxylic Acid, 1-Isocyanato-, Methyl Ester (9Ci) is a specialized isocyanate derivative of cyclopropane, serving as a critical building block for introducing the strained, bioactive cyclopropane ring into advanced molecular architectures. This compound matters for its unique reactivity profile, enabling the synthesis of novel compounds with potential applications in pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the metabolic stability conferred by the cyclopropane ring.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental persistence.
• Polymer Modification: Serves as a reactive monomer or cross-linking agent for producing specialty polyurethanes and polyurea coatings with tailored mechanical and chemical resistance properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes and affinity labels for studying enzyme function and protein interactions in biochemical research.
• Ligand and Catalyst Development: A precursor for synthesizing chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Investigated for incorporation into advanced polymeric materials to modify thermal stability, rigidity, and surface characteristics.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Isocyanato-, Methyl Ester (9Ci)
CAS No.	76126-48-2
Molecular Formula	C6H7NO3
Molecular Weight	141.13 g/mol
Synonyms	Methyl 1-Isocyanatocyclopropanecarboxylate; 1-Isocyanatocyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic Acid, 1-Isocyanato-, Methyl Ester; Methyl (1-Isocyanatocyclopropyl)formate; Cyclopropane-1-carboxylic acid, 1-isocyanato-, methyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Isocyanato-, Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and IR/NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.