Description

Methyl 1-Trityl-1H-Imidazole-4-Carboxylate is a high-purity, protected imidazole derivative primarily used as a sophisticated synthetic intermediate in advanced organic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for constructing complex heterocyclic systems. It is essential for pharmaceutical R&D, particularly in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals where the trityl protecting group offers strategic synthetic advantages.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those containing imidazole-based pharmacophores.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and plant growth regulators that utilize heterocyclic chemistry.
• Fine Chemical Production: Serves as a precursor for synthesizing complex ligands, catalysts, and specialty materials used in various chemical processes.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, particularly in studies involving protecting group strategies and heterocycle functionalization.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptide analogs and mimetics where the imidazole moiety is a critical functional element.

Basic Information

Item	Details
Product Name	Methyl 1-Trityl-1H-Imidazole-4-Carboxylate
CAS No.	76074-88-9
Molecular Formula	C24H20N2O2
Molecular Weight	368.43 g/mol
Synonyms	1-Trityl-1H-imidazole-4-carboxylic acid methyl ester; Methyl 1-tritylimidazole-4-carboxylate; 1H-Imidazole-4-carboxylic acid, 1-(triphenylmethyl)-, methyl ester; Methyl 1-(triphenylmethyl)-1H-imidazole-4-carboxylate; Trityl-protected imidazole carboxylate; 1-Tritylimidazole-4-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1-Trityl-1H-Imidazole-4-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.