Description

2-Bromo-3-Methoxy-6-Nitropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique reactivity profile, where the bromo, methoxy, and nitro substituents on the pyridine ring offer distinct sites for selective functionalization, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and photoactive materials.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, allowing for further derivatization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-Bromo-3-Methoxy-6-Nitropyridine
CAS No.	76066-07-4
Molecular Formula	C6H5BrN2O3
Molecular Weight	233.02 g/mol
Synonyms	2-Bromo-3-methoxy-6-nitropyridine; 3-Methoxy-6-nitro-2-bromopyridine; 2-Bromo-3-methoxynitropyridine; Pyridine, 2-bromo-3-methoxy-6-nitro-; 6-Nitro-2-bromo-3-methoxypyridine; 2-Bromo-3-methoxy-6-nitro-pyridine; 2-Br-3-MeO-6-NO2-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxy-6-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.