Description

2-Chloro-5-[3-(Trifluoromethyl)Phenyl]-Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of the pyridine scaffold with chloro and trifluoromethylphenyl substituents, enabling precise molecular modifications for developing novel compounds with targeted properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of receptor modulators and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for creating specialized ligands, organic electronic materials, and liquid crystals.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and process development.

Basic Information

Product Name	2-Chloro-5-[3-(Trifluoromethyl)Phenyl]-Pyridine
CAS No.	76053-50-4
Molecular Formula	C12H7ClF3N
Molecular Weight	257.64 g/mol
Synonyms	2-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine; 2-Chloro-5-(α,α,α-trifluoro-m-tolyl)pyridine; 5-(3-Trifluoromethylphenyl)-2-chloropyridine; 2-Chloro-5-(3-trifluoromethylphenyl)pyridine; 2-Chloro-5-(m-trifluoromethylphenyl)pyridine; 2-Chloro-5-(3-trifluoromethyl-phenyl)pyridine; 2-Chloro-5-(3-trifluoromethylphenyl)pyridine (76053-50-4)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-[3-(Trifluoromethyl)Phenyl]-Pyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.