Description

2-Oxo-5-[3-(Trifluoromethyl)Phenyl]-1,2-Dihydro-3-Pyridinecarbonitrile is a high-value, multi-functional heterocyclic building block featuring a trifluoromethylphenyl substituent. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for its utility as a key intermediate in the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridone and trifluoromethyl motifs.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, organic semiconductors, or liquid crystals.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and structure-activity relationships (SAR).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring this specific scaffold.

Basic Information

Product Name	2-Oxo-5-[3-(Trifluoromethyl)Phenyl]-1,2-Dihydro-3-Pyridinecarbonitrile
CAS No.	76053-36-6
Molecular Formula	C13H7F3N2O
Molecular Weight	264.21 g/mol
Synonyms	5-(3-(Trifluoromethyl)phenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-5-[3-(trifluoromethyl)phenyl]-2(1H)-pyridinone; 5-(α,α,α-Trifluoro-m-tolyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 76053-36-6; 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-[3-(trifluoromethyl)phenyl]-; 5-(3-Trifluoromethylphenyl)-2-oxo-1,2-dihydronicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Oxo-5-[3-(Trifluoromethyl)Phenyl]-1,2-Dihydro-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.