Description

Reclazepam CAS NO 76053-16-2 is a high-purity benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the discovery of new anxiolytic, sedative, or anticonvulsant medications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing via HPLC, GC, or LC-MS.
• Biochemical Research: Employed in preclinical studies to investigate pharmacological activity, receptor binding affinity, and metabolic pathways.
• Process Development: Utilized in scaling up synthetic routes and optimizing manufacturing processes under GMP conditions.
• Impurity Profiling: Acts as a marker or impurity standard to ensure the purity and safety profile of final drug substances.

Basic Information

Product Name	Reclazepam
CAS No.	76053-16-2
Molecular Formula	C₁₇H₁₄ClN₃O₂
Molecular Weight	327.76 g/mol
Synonyms	Reclazepam; 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 05-2921; Ro 05-2921/000; Ro 05-2921/001; Ro05-2921
EINECS	Contact for details

Quality Control

Our Reclazepam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements of pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.