Description

3-Chloro-2-Hydroxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique combination of chlorine, hydroxyl, and trifluoromethyl substituents. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts critical biological activity and favorable physicochemical properties. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core and trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas requiring fluorine-containing motifs for enhanced metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex heterocyclic systems and exploring novel chemical reactions.
• Fine Chemical Production: An intermediate in the multi-step synthesis of other high-value specialty chemicals and performance materials.

Basic Information

Product Name	3-Chloro-2-Hydroxy-5-(Trifluoromethyl)Pyridine
CAS No.	76041-71-9
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	2-Hydroxy-3-chloro-5-(trifluoromethyl)pyridine; 3-Chloro-5-(trifluoromethyl)pyridin-2-ol; 3-Chloro-2-hydroxy-5-trifluoromethylpyridine; 5-(Trifluoromethyl)-3-chloropyridin-2-ol; 2-Pyridinol, 3-chloro-5-(trifluoromethyl)-; 76041-71-9; 3-Chloro-5-trifluoromethyl-2-hydroxypyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 3-Chloro-2-Hydroxy-5-(Trifluoromethyl)Pyridine is monitored through in-process checks and final batch analysis using advanced techniques like HPLC, GC, and NMR to ensure consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.