Description

n-[n-[n-(3-Hydroxy-4-Methyl-1-Oxodecyl)-L-Valyl]-L-Phenylalanyl]-D-Isoleucine λ-Lactone is a complex, cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block (synthon) or intermediate for synthesizing novel peptide-based therapeutics and bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the discovery of new drugs, particularly in areas targeting specific enzymatic pathways or receptor interactions.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of complex peptide drugs and investigational new chemical entities.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to explore biological pathways and mechanisms of action.
• Peptide Library Synthesis: Serves as a specialized monomer for constructing diverse peptide libraries in combinatorial chemistry for drug screening.
• Protease Inhibitor Development: Potential core structure for designing novel inhibitors targeting specific proteases due to its lactone functionality and peptide backbone.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for advanced material science.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, medicinal chemistry, and peptide science.

Basic Information

Product Name	n-[n-[n-(3-Hydroxy-4-Methyl-1-Oxodecyl)-L-Valyl]-L-Phenylalanyl]-D-Isoleucine λ-Lactone
CAS No.	75947-02-3
Molecular Formula	C32H49N3O6
Molecular Weight	571.75 g/mol
Synonyms	D-Isoleucine, N-[N-[N-(3-hydroxy-4-methyl-1-oxodecyl)-L-valyl]-L-phenylalanyl]-, λ-lactone; (3S,6S,9S,12R)-3-[(2S)-2-Hydroxy-3-methylbutyl]-6-isobutyl-9-benzyl-4,7,10-trioxo-1-oxa-4,7,10-triazacyclododec-12-yl 3-hydroxy-4-methyl-decanoate; Cyclo(L-valyl-L-phenylalanyl-D-isoleucine) derivative; 75947-02-3; Peptide lactone intermediate; L-Val-L-Phe-D-Ile lactone derivative.
EINECS	Contact for details

Quality Control

Our n-[n-[n-(3-Hydroxy-4-Methyl-1-Oxodecyl)-L-Valyl]-L-Phenylalanyl]-D-Isoleucine λ-Lactone is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.