Description

Arteether CAS NO 75887-54-6 is a potent semi-synthetic derivative of artemisinin, a key antimalarial compound. It is valued for its efficacy against severe and multidrug-resistant strains of *Plasmodium falciparum* malaria. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry developing injectable and oral formulations for global health initiatives.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral antimalarial drugs.
• Treatment of Severe Malaria: Critical component in formulations for the management of complicated and cerebral malaria.
• Combination Therapies: Used in Artemisinin-based Combination Therapies (ACTs) to combat drug resistance.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for protozoal infections.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and parasitological research.
• Public Health Procurement: Supplied for large-scale manufacturing of medicines for WHO-prequalified and national disease control programs.

Basic Information

Product Name	Arteether
CAS No.	75887-54-6
Molecular Formula	C17H28O5
Molecular Weight	312.40 g/mol
Synonyms	Artemotil; Dihydroartemisinin Ethyl Ether; β-Arteether; Arteether B; Artemisinin Ethyl Ether; 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, ethyl ether, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, ethyl ether
EINECS	Contact for details

Quality Control

Our Arteether is manufactured under strict quality management systems, targeting compliance with pharmaceutical grade standards such as ICH Q7 and WHO GMP. Each batch undergoes comprehensive analytical testing including HPLC for assay and related substances, residual solvent analysis, and specific identification. A Certificate of Analysis (COA) documenting purity, identity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.