Description

Methyl 4-(2-(Trimethylsilyl)Ethynyl)Benzoate is a specialized organic building block featuring a benzoate ester core functionalized with a trimethylsilyl-protected ethynyl group. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, especially those requiring conjugated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate acetylene-linked aromatic motifs.
• Material Science & OLEDs: Acts as a precursor for organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials where extended π-conjugation is desired.
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Heck, and other palladium-catalyzed coupling reactions due to the reactive ethynyl group.
• Liquid Crystal & Polymer Synthesis: Employed in the creation of monomers for specialty polymers and liquid crystal displays (LCDs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and molecular scaffolds.

Basic Information

Product Name	Methyl 4-(2-(Trimethylsilyl)Ethynyl)Benzoate
CAS No.	75867-41-3
Molecular Formula	C13H16O2Si
Molecular Weight	232.35 g/mol
Synonyms	Methyl 4-[(trimethylsilyl)ethynyl]benzoate; Benzoic acid, 4-[(trimethylsilyl)ethynyl]-, methyl ester; 4-((Trimethylsilyl)ethynyl)benzoic acid methyl ester; Methyl p-((trimethylsilyl)ethynyl)benzoate; Methyl 4-(trimethylsilylethynyl)benzoate; TMS-Ethynyl Benzoate Methyl Ester; 75867-41-3
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(2-(Trimethylsilyl)Ethynyl)Benzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.