Description

2-Bromo-5-Chloro-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and nitrated pyridine structure makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromo and chloro substituents.
• Nucleophilic Aromatic Substitution: The nitro and halogen groups activate the pyridine ring for selective substitution, enabling diverse chemical modifications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Nitropyridine
CAS No.	75806-86-9
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	5-Chloro-2-bromo-3-nitropyridine; 3-Nitro-2-bromo-5-chloropyridine; 2-Bromo-5-chloro-3-nitro-pyridine; Pyridine, 2-bromo-5-chloro-3-nitro-; 75806-86-9; BCPN; 2-Br-5-Cl-3-NO2-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-3-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.