Description

Ethinyl Estradiol-17-Sulfate is a key sulfated metabolite of the synthetic estrogen ethinyl estradiol. This compound is of significant importance in pharmaceutical research and development, particularly in the study of metabolic pathways, drug-drug interactions, and hormone-related therapies. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity compounds for analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and qualification of ethinyl estradiol metabolites in bioanalytical studies, supporting drug development and pharmacokinetic research.
• Metabolic Pathway Research: Essential for investigating the phase II sulfation metabolism of synthetic estrogens, aiding in the understanding of drug clearance and potential interactions.
• Diagnostic Reagent Manufacturing: Serves as a high-purity raw material or calibrator in the production of diagnostic kits and assays for hormonal analysis.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in endocrinology, toxicology, and analytical chemistry method development.
• Impurity Profiling: Acts as a known impurity or degradation product standard in the quality control of ethinyl estradiol-containing pharmaceutical formulations.

Basic Information

Product Name	Ethinyl Estradiol-17-Sulfate
CAS No.	75803-36-0
Molecular Formula	C20H24O5S
Molecular Weight	376.47 g/mol
Synonyms	19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol 17-Sulfate; Ethinylestradiol 17-Sulfate; EE2-17-Sulfate; 17β-Ethinylestradiol 17-Sulfate; Ethynylestradiol Sulfate; NSC 338947
EINECS	Contact for details

Quality Control

Our Ethinyl Estradiol-17-Sulfate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is assured through a comprehensive battery of analytical tests, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, ensuring compliance with rigorous research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect this light-sensitive and potentially hygroscopic compound from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.