Description

6-Chloro-5-Methoxypyridine-3-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, making it a critical intermediate in the development of complex, high-value molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine-sulfonyl chloride scaffold.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialized polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes targeting specific proteins.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Chloro-5-Methoxypyridine-3-Sulfonyl Chloride
CAS No.	75720-93-3
Molecular Formula	C6H5Cl2NO3S
Molecular Weight	250.08 g/mol
Synonyms	3-Chlorosulfonyl-6-chloro-5-methoxypyridine; 6-Chloro-5-methoxy-3-pyridinesulfonyl chloride; 5-Methoxy-6-chloropyridine-3-sulfonyl chloride; 6-Chloro-5-methoxypyridine-3-sulfonylchloride; 3-Pyridinesulfonyl chloride, 6-chloro-5-methoxy-; 75720-93-3; 6-Chloro-5-methoxypyridin-3-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Methoxypyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.