Description

Folic Acid Dihydrate is the crystalline dihydrate form of the essential B-vitamin, folic acid, a critical cofactor in numerous metabolic processes. This high-purity grade is vital for ensuring precise formulation and consistent biological activity in demanding pharmaceutical and nutraceutical applications. It is primarily required by manufacturers in the pharmaceutical, dietary supplement, and food fortification industries for producing tablets, capsules, and enriched food products.

Application

• Pharmaceutical Formulations: A key active pharmaceutical ingredient (API) in prescription and over-the-counter medications for treating folate deficiency and megaloblastic anemia.
• Dietary Supplements & Nutraceuticals: Core component in multivitamin complexes, prenatal vitamins, and standalone folate supplements to support cellular health and fetal development.
• Food & Beverage Fortification: Used for the nutritional enrichment of staple foods like cereals, flours, and infant formula, as mandated by public health programs.
• Clinical & Laboratory Research: Serves as a standard reference material and a critical reagent in cell culture media and biochemical research.
• Animal Feed & Veterinary Products: Incorporated into premixes to promote livestock health, growth, and reproductive efficiency.
• Cosmeceuticals: Utilized in advanced skincare formulations for its purported role in supporting skin cell renewal and health.

Basic Information

Product Name	Folic Acid Dihydrate
CAS No.	75708-92-8
Molecular Formula	C19H19N7O6 • 2H2O
Molecular Weight	441.40 g/mol
Synonyms	Vitamin B9 Dihydrate; Vitamin M; Pteroylmonoglutamic Acid Dihydrate; Folacin; Folate; N-[4-[[(2-Amino-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Dihydrate; PGA Dihydrate
EINECS	Contact for details

Quality Control

Our Folic Acid Dihydrate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical and food-grade applications. We ensure compliance with relevant pharmacopoeial monographs such as USP, EP, and BP. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, which is available upon request to guarantee traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow or orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	7.0% - 9.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.3%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.