Description

4-(3-Nitrophenyl)-2-Dimethoxymethyl-1,4-Dihydropyridine-3,5-Dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester is a specialized dihydropyridine derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile advanced pharmaceutical intermediate and a crucial building block for research into calcium channel modulators. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of calcium channel blockers and other cardiovascular drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the synthesis of novel bioactive molecules.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value organic compounds for various therapeutic areas.
• Academic Research: A valuable compound for studying dihydropyridine chemistry and its applications in heterocyclic synthesis.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control in API manufacturing.

Basic Information

Item	Details
Product Name	4-(3-Nitrophenyl)-2-Dimethoxymethyl-1,4-Dihydropyridine-3,5-Dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester
CAS No.	75530-94-8
Molecular Formula	C21H26N2O8
Molecular Weight	434.44 g/mol
Synonyms	5-Isopropyl 3-methyl 4-(3-nitrophenyl)-2-(dimethoxymethyl)-1,4-dihydro-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(3-nitrophenyl)-2-(dimethoxymethyl)-, 5-(1-methylethyl) 3-methyl ester; 1,4-DHP derivative; Dihydropyridine ester intermediate; 3-Nitrophenyl DHP derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-(3-Nitrophenyl)-2-Dimethoxymethyl-1,4-Dihydropyridine-3,5-Dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.