Description

Spiro[2.2]Pentane, Bromo- (9Ci) is a specialized brominated spirocyclic organic compound with the CAS registry number 75522-03-1. This unique spiro structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for introducing constrained, three-dimensional frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

The unique steric and electronic properties of Bromospiro[2.2]pentane make it suitable for several high-value synthetic applications:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those requiring rigid, three-dimensional scaffolds to improve binding affinity and metabolic stability.
• Agrochemical Research: Used in developing new pesticides and herbicides where the spirocyclic core can contribute to unique biological activity and environmental profile.
• Ligand and Catalyst Development: Acts as a backbone for constructing sophisticated phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science: Employed in the synthesis of specialty polymers and advanced organic electronic materials that benefit from its rigid, non-planar geometry.
• Cross-Coupling Reactions: Functions as an alkylating agent in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to incorporate the spiro[2.2]pentane moiety into complex molecules.

Basic Information

Product Name	Spiro[2.2]Pentane, Bromo- (9Ci)
CAS No.	75522-03-1
Molecular Formula	C5H7Br
Molecular Weight	147.01 g/mol
Synonyms	1-Bromospiro[2.2]pentane; Bromospiro[2.2]pentane; Spiro[2.2]pentane, 1-bromo-; 1-Bromo-spiro[2.2]pentane; NSC 169102; 75522-03-1
EINECS	Contact for details

Quality Control

Our Spiro[2.2]Pentane, Bromo- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 94.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.