Description

1,2,3,3-Tetramethyl-2-Azabicyclo(2.2.2)Octan-5-trans-Ol p-Methylbenzoa Te is a high-purity, specialized bicyclic amine derivative with a complex stereochemical structure. This compound is valued for its role as a critical chiral building block and intermediate in advanced organic synthesis. It is primarily required by research institutions and pharmaceutical development companies working on novel active pharmaceutical ingredients (APIs), complex natural product analogs, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Catalysis: Used as a precursor or ligand in the synthesis of catalysts for stereoselective chemical transformations.
• Agrochemical Research: Serves as a building block for novel, high-efficacy crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in methodological studies and the synthesis of complex molecular architectures in chemistry laboratories.
• Fine Chemical Synthesis: Integral to the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	1,2,3,3-Tetramethyl-2-Azabicyclo(2.2.2)Octan-5-trans-Ol p-Methylbenzoa Te
CAS No.	75479-61-7
Molecular Formula	C19H27NO2
Molecular Weight	301.43 g/mol
Synonyms	5-trans-Hydroxy-1,2,3,3-tetramethyl-2-azabicyclo[2.2.2]octane p-methylbenzoate; 2-Azabicyclo[2.2.2]octan-5-ol, 1,2,3,3-tetramethyl-, 5-(4-methylbenzoate), (5R)-; (1R,4R,5R)-1,2,3,3-Tetramethyl-2-azabicyclo[2.2.2]octan-5-yl 4-methylbenzoate; Troger's Base derivative; TMB-Ol p-Methylbenzoate; Bicyclic tertiary amine ester.
EINECS	Contact for details

Quality Control

Every batch of our 1,2,3,3-Tetramethyl-2-Azabicyclo(2.2.2)Octan-5-trans-Ol p-Methylbenzoa Te is manufactured and tested under a strict quality management system. We guarantee high chemical and isomeric purity, with comprehensive analytical characterization including HPLC, GC, NMR, and chiral analysis to confirm identity and potency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.