Description

4,4-Dimethylspiro[7-Oxabicyclo[4.1.0]Heptane-3,1'-Cyclobutan]-2'-One is a high-purity, specialized spirocyclic organic compound with the CAS registry number 75314-18-0. This molecule is valued for its unique structural framework, which makes it a versatile and critical advanced intermediate in sophisticated organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity and environmental profile.
• Material Science Research: Investigated as a monomer or precursor for developing polymers with specific thermal or optical properties due to its rigid, oxygen-containing bicyclic structure.
• Organic Synthesis Reagent: Acts as a sophisticated electrophile or scaffold in multi-step synthetic routes for creating complex natural product analogs and other fine chemicals.
• Ligand and Catalyst Development: Explored in academic and industrial R&D for constructing novel chiral ligands or catalyst frameworks for asymmetric synthesis.

Basic Information

Product Name	4,4-Dimethylspiro[7-Oxabicyclo[4.1.0]Heptane-3,1'-Cyclobutan]-2'-One
CAS No.	75314-18-0
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	4,4-Dimethylspiro[7-oxabicyclo[4.1.0]heptane-3,1'-cyclobutan]-2'-one; 2'-Oxo-4,4-dimethylspiro[7-oxabicyclo[4.1.0]heptane-3,1'-cyclobutane]; Spiro[7-oxabicyclo[4.1.0]heptane-3,1'-cyclobutan]-2'-one, 4,4-dimethyl-; 75314-18-0; 4,4-Dimethylspiro(7-oxabicyclo(4.1.0)heptane-3,1'-cyclobutan)-2'-one
EINECS	Contact for details

Quality Control

Our production of 4,4-Dimethylspiro[7-Oxabicyclo[4.1.0]Heptane-3,1'-Cyclobutan]-2'-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.