Description

2-Chloro-5-Fluoronicotinamide is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its functionalized pyridine ring, which serves as a critical building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated nicotinamide structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and enzyme inhibitors used in biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoronicotinamide
CAS No.	75302-64-6
Molecular Formula	C6H4ClFN2O
Molecular Weight	174.56 g/mol
Synonyms	2-Chloro-5-fluoropyridine-3-carboxamide; 3-Carbamoyl-2-chloro-5-fluoropyridine; 5-Fluoro-2-chloronicotinamide; Nicotinamide, 2-chloro-5-fluoro-; 2-Chloro-5-fluoro-3-pyridinecarboxamide; 2-Chloro-5-fluoronicotinic acid amide
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoronicotinamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.