Description

12,13-Bis[(Trimethylsilyl)Oxy]-9-Octadecenoic Acid Methyl Ester is a high-value, protected derivative of oleic acid, featuring trimethylsilyl (TMS) groups that enhance its stability and reactivity for advanced synthetic applications. This compound serves as a crucial protected intermediate in organic synthesis, allowing for selective chemical transformations that are essential for producing complex molecules. It is primarily sought by pharmaceutical research and fine chemical industries for the development of specialized lipids, bioactive compounds, and novel materials.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of complex lipid-based drug candidates, prostaglandin analogs, and other bioactive molecules.
• Organic Synthesis Reagent: Used in multi-step synthesis where the protection of hydroxyl groups is required to control regioselectivity and prevent unwanted side reactions.
• Lipid Chemistry Research: Serves as a model compound or building block in academic and industrial research focused on modified fatty acids and their derivatives.
• Fine Chemical Production: Employed in the manufacture of high-purity specialty chemicals, including surfactants, lubricant additives, and polymer precursors with tailored properties.
• Reference Standard: Used as an analytical standard in chromatography (GC, HPLC) for quality control and method development in laboratories.

Basic Information

Product Name	12,13-Bis[(Trimethylsilyl)Oxy]-9-Octadecenoic Acid Methyl Ester
CAS No.	75299-46-6
Molecular Formula	C25H52O4Si2
Molecular Weight	472.86 g/mol
Synonyms	Methyl 12,13-Bis(trimethylsilyloxy)-9-octadecenoate; 9-Octadecenoic Acid, 12,13-Bis[(trimethylsilyl)oxy]-, Methyl Ester; Methyl Oleate 12,13-Bis(TMS) Ether; 12,13-Di-O-trimethylsilyl Methyl Oleate; TMS-protected Methyl Oleate Derivative; 12,13-Bis(trimethylsiloxy)-9-octadecenoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 12,13-Bis[(Trimethylsilyl)Oxy]-9-Octadecenoic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.