Description

5,6-Dichloronicotinamide is a versatile halogenated nicotinamide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive dichloro-substituted pyridine ring, which provides distinct sites for selective functionalization and ring modification. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, including potential active ingredients and novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Chemical Research: A valuable reagent in academic and industrial laboratories for studying heterocyclic chemistry, cross-coupling reactions, and nucleophilic substitution patterns.
• Material Science Precursor: Potential starting material for creating functionalized ligands, organic semiconductors, or metal-organic frameworks (MOFs).
• Custom Synthesis: Serves as a specialized substrate for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	5,6-Dichloronicotinamide
CAS No.	75291-84-8
Molecular Formula	C6H4Cl2N2O
Molecular Weight	191.01 g/mol
Synonyms	5,6-Dichloropyridine-3-carboxamide; 3-Carbamoyl-5,6-dichloropyridine; 5,6-Dichloronicotinic acid amide; 5,6-Dichloro-3-pyridinecarboxamide; Nicotinamide, 5,6-dichloro-; 5,6-Dichloro-3-carbamoylpyridine; 5,6-Dichloronicotinamide (75291-84-8)
EINECS	Contact for details

Quality Control

Our 5,6-Dichloronicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development applications, and specifications can be adjusted to support cGMP or other regulatory needs upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.