Description

5-Bromo-6-Chloronicotinamide is a high-purity halogenated nicotinamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacologically active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce functional complexity.
• Material Science Research: Potential monomer or precursor for designing functional organic materials and ligands for metal-organic frameworks (MOFs).
• Biochemical Probe Development: Useful for creating labeled compounds or probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Bromo-6-Chloronicotinamide
CAS No.	75291-83-7
Molecular Formula	C6H4BrClN2O
Molecular Weight	235.47 g/mol
Synonyms	6-Chloro-5-bromonicotinamide; Nicotinamide, 5-bromo-6-chloro-; 5-Bromo-6-chloro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 5-bromo-6-chloro-; 5-Br-6-Cl-nicotinamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloronicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.