Description

(S)-2-(Benzyloxycarbonylamino)-3-Butenoic Acid Methyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role in constructing complex peptide mimetics and biologically active molecules with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and other peptidomimetic drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Peptidomimetic Research: Used to introduce the dehydroamino acid moiety into peptide chains to study conformation-activity relationships.
• Asymmetric Synthesis: Serves as a versatile building block for the preparation of non-natural amino acids and other chiral compounds.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Chemical Biology: Utilized in the synthesis of activity-based probes and labeled peptides for biochemical assays.

Basic Information

Product Name	(S)-2-(Benzyloxycarbonylamino)-3-Butenoic Acid Methyl Ester
CAS No.	75266-40-9
Molecular Formula	C₁₃H₁₅NO₄
Molecular Weight	249.26 g/mol
Synonyms	Methyl (S)-2-(((benzyloxy)carbonyl)amino)but-3-enoate; (S)-2-(Cbz-Amino)-3-butenoic Acid Methyl Ester; (S)-N-Cbz-2-Amino-3-butenoic Acid Methyl Ester; (S)-2-((Benzyloxycarbonyl)amino)-3-butenoic Acid Methyl Ester; Z-(S)-AABA-OMe; Z-(S)-2-Amino-3-butenoic Acid Methyl Ester; (S)-2-(Benzyloxycarbonylamino)-3-butenoate Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-2-(Benzyloxycarbonylamino)-3-Butenoic Acid Methyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.